The Effect Of Sleep Deprivation On Seizure - 1220 Words

A study on the effect of sleep deprivation on seizure in epilepsy disorder and its relation to signaling bathways in the brain People with seizure disorder usually have problems with their sleep. Daytime sleepiness, lack of energy and drowsiness are frequently seen in epileptic patients. Baseline electrical activity has been vastly studied in epilepsy. Seizures can be either partial or generalized. Based on the area of the brain triggered by epileptic waves, any kind of motor or sensory abnormalities can happen in partial seizure. If the whole brain cortex is triggered, generalized tonic-clonic seizure can happen, which is the classic shaking of the body and loss of consciousness. Generalized seizures may be followed by a post-ictal period in which the patient will be heavily drowsy and may experience memory loss for a short amount of time. It has been shown that epileptic patients can reach threshold potentials more readily than the normal population and lack of sleep can be a trigger for causing a seizure [1]. The circadian rhythm, synchronizing role of thalamo-cortical networks, and reduced intracortical inhibition have been suggested as underlying physiologic factors elicited by sleep deprivation that make a patient more prone to seizure activity. The abnormal progress from resting potential to a wild epileptic wave can be triggered by sleep deprivation as lack of sleep alters the neural resting potential. Seizure occurrence is found to be related to the circadianShow MoreRelatedWhy We Sleep- The Pending Mystery 731 Words   |  3 Pagesinto the field of sleep research. However, these discoveries are still far from being complete. Considering that an individual spends about one-third of their life sleeping, there is much more that still needs to be discovered concerning this topic. 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